radically, profoundly, inherently, completely, totally, substantively, structurally, intrinsically, vastly, philosophically, demonstrably, unalterably, utterly, entirely, conceptually, massively, endemically, basically, morally, essentially, dramatically, wholly, broadly, irrevocably, truly, innately, drastically, per se, clearly, materially, diametrically, manifestly, frankly, terribly, observably, irreparably, qualitatively, determinately, materialistically, conventional wisdom, prescriptively, irreversibly, catastrophically, genuinely, inflexibly, perniciously, vitally, substantially, certainly, superficially, institutionally, irredeemably, patently, markedly, obviously, irremediably, dialectically, dogmatically, necessarily, status quo, ideologically, really, enormously, irreconcilably, paradigm shift, doctrinally, zero sum, unambiguously, intractably, logically, simply, tangibly, plainly, ontologically, hugely, grossly, uniquely, intellectually, significantly, absolutely, secularly, probabilistically, deeply, technologically, insofar, starkly, pragmatically, ultimately, somewhat, broadly speaking, organizationally, differently, mechanistically, meaningfully, unquestionably, gaia hypothesis, technically, horribly, precisely, palpably, immutably, infinitely

disparate, larva

au fond, in essence