Definitions of Seneca:
- noun: the Iroquoian language spoken by the Seneca people
- noun: a member of the Iroquoian people formerly living in New York state south of Lake Ontario
- noun: Roman statesman and philosopher who was an advisor to Nero; his nine extant tragedies are modeled on Greek tragedies (circa 4 BC - 65 AD)
- name: A surname (very rare: popularity rank in the U.S.: #23398)