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Definitions of roofie:
  • noun:   (slang, often in the plural) Rohypnol.
  • noun:   (slang, by extension) Any drug designed to make someone drowsy or disoriented; a date rape drug.
  • verb:   (slang, transitive) To put roofies in; to spike with roofies.
  • verb:   (slang, transitive) To cause someone to (usually unknowingly) ingest roofies.

(Definitions from Wiktionary)

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