Definitions of puffer:

• noun:   any of numerous marine fishes whose elongated spiny body can inflate itself with water or air to form a globe; several species contain a potent nerve poison; closely related to spiny puffers
• noun:   delicacy that is highly dangerous because of a potent nerve poison in ovaries and liver
• name:  A surname (rare: 1 in 100000 families; popularity rank in the U.S.: #15700)