Definitions of nettle:

• noun:   any of numerous plants having stinging hairs that cause skin irritation on contact (especially of the genus Urtica or family Urticaceae)
• verb:   sting with or as with nettles and cause a stinging pain or sensation
• verb:   cause annoyance in; disturb, especially by minor irritations
• name:  A surname (very rare: popularity rank in the U.S.: #50242)