Definitions of cuff:

• noun:   the lap consisting of a turned-back hem encircling the end of the sleeve or leg
• noun:   shackle that consists of a metal loop that can be locked around the wrist; usually used in pairs
• verb:   hit with the hand
• verb:   confine or restrain with or as if with manacles or handcuffs

  Example: "The police handcuffed the suspect at the scene of the crime"

• name:  A surname (rare: 1 in 100000 families; popularity rank in the U.S.: #9988)