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Definitions of opioid:
  • noun:   A substance that has effects similar to opium.
  • noun:   (physiology) Any of the natural substances, such as an endorphin, released in the body in response to pain.
  • noun:   (pharmacology) Any of a group of synthetic compounds that exhibit similarities to the opium alkaloids that occur in nature.

(Definitions from Wiktionary)

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