Definitions of pioneer:

• noun:   one the first colonists or settler in a new territory

  Example: "They went west as pioneers with only the possessions they could carry with them"

• noun:   someone who helps to open up a new line of research or technology or art
• verb:   open up and explore a new area

  Example: "Pioneer space"

• verb:   open up an area or prepare a way

  Example: "She pioneered a graduate program for women students"

• verb:   take the lead or initiative in; participate in the development of

  Example: "This South African surgeon pioneered heart transplants"